Clinical Data Management (Advanced)
Job Description
Clinical Data Management
ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
We are seeking an experienced Advanced Clinical Data Manager (CDM) to lead and perform complex scientific clinical data review activities across clinical programs. In this role, you will work in close collaboration with Study Responsible Physicians (SRP), Study Responsible Scientists (SRS), and cross-functional teams to ensure high-quality, scientifically robust, and inspection-ready clinical data.
You will play a program-level leadership role, driving data review strategy, ensuring compliance with regulatory requirements (ICH-GCP, SOPs), and contributing to continuous improvement initiatives within Clinical Data Management.
What You Will Do:
- Lead and execute complex scientific clinical data review at both trial and program levels.
- Collaborate closely with SRP/SRS to review data, resolve eDC queries, and ensure data accuracy and completeness.
- Oversee data flows and Data Management Plans while performing continuous, in-depth data review activities.
- Contribute to protocol design and provide input into eCRFs and data collection tools.
- Align data review expectations and timelines with SRP/SRS, GDM, CROs, and cross-functional stakeholders.
- Define data quality standards, conventions, and ensure timely delivery of all CDM milestones.
- Develop and maintain key documents such as the Integrated Review Plan, ensuring regulatory compliance.
- Ensure inspection readiness and actively support audits and health authority inspections.
- Provide program-level leadership by supporting DMLs in planning, resource allocation, and cross-functional collaboration.
- Drive quality and continuous improvement by implementing best practices and leading process, system, and tool enhancements.
Your Profile:
- Bachelor’s degree in Life Sciences or related field with 5+ years of Clinical Data Management experience, including strong expertise in scientific data review.
- Solid experience in clinical drug development with deep understanding of data flows, data review processes, and ICH-GCP regulatory requirements.
- Proven leadership capabilities at study or program level, with experience in stakeholder and resource management.
- Strong collaboration skills with the ability to work effectively with physicians, scientists, CROs, and global cross-functional teams.
- Proficiency in eDC and clinical data systems, combined with strong analytical, communication, and problem-solving skills and a quality-driven, continuous improvement mindset.
What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our benefits examples include:
- Various annual leave entitlements
- A range of health insurance offerings to suit you and your family’s needs.
- Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
- Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
- Life assurance
- Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here to apply